Cellular therapy (CT) is the transplantation of human cells to replace or repair damaged tissue and/or cells. With new technologies, innovative products, and limitless imagination, many different types of cells may be used as part of a therapy or treatment for a variety of diseases and conditions.
TriLink offers several Cas9 mRNA variations for CAR-T cell therapy using CRISPR Technology. These mRNAs are unmodified or modified with 5-methoxyuridine (5moU) to reduce innate immune responses. These have been sequence optimized with the help of leading researchers in the field of optimal expression. When you are ready to move your research to the clinic, TriLink offers cGMP synthesis of guide strands and nuclease mRNAs in our purpose built cGMP facility.
Reagents for CAR-T Editing: