TriLink CleanTag® technology eliminates the need for adapter-dimer removal to enable quick, easy small RNA library preparation from low-input samples. Use CleanTag primer sets and kits to produce clean NGS libraries for miRNA sequencing from as little as 100 pg total RNA or from single cells.
Adapter dimers form when 5' and 3' adapters self-ligate the target library insert, and amplification of this smaller adapter dimer side product often exceeds amplification of the tagged library. Our modified adapters block adapter-adapter ligation to improve the ratio of adapter dimer to tagged library. This improves the quality of sequencing data.
Use CleanTag products to: